Kliniken und Institute


Institut für Molekulare Onkologie


Dobbelstein

Leitung

Direktor des Instituts
Prof. Dr. Matthias Dobbelstein

Sekretariat

Telefon: +49 (0) 551 39-13860
Fax: +49 (0) 551 39-13713
E-Mail: kmetze@gwdg.de

Anschrift

Justus-von-Liebig-Weg 11
37077 Göttingen

Homepage

URL / Homepage www.moloncol.med.uni-goettingen.de

Downloads

PDF Publikationen 2015 2014 2013 2012 2011

Ausgewählte Publikationen
  • Zhang X, Schulz R, Edmunds S, Krüger E, Markert E, Gaedcke J, Cormet-Boyaka E, Ghadimi M, Beissbarth T, Levine AJ, Moll UM, Dobbelstein M: MicroRNA-101 Suppresses Tumor Cell Proliferation by Acting as an Endogenous Proteasome Inhibitor via Targeting the Proteasome Assembly Factor POMP. Mol Cell. 2015 Jul 16;59(2):243-57. doi: 10.1016/j.molcel.2015.05.036. Epub 2015 Jul 2. (http://www.ncbi.nlm.nih.gov/pubmed/26145175)
  • Alexandrova EM, Yallowitz AR, Li D, Xu S, Schulz R, Proia DA, Lozano G, Dobbelstein M, Moll UM: Improving survival by exploiting tumour dependence on stabilized mutant p53 for treatment. Nature. 2015 Jul 16;523(7560):352-6. doi: 10.1038/nature14430. Epub 2015 May 25. (http://www.ncbi.nlm.nih.gov/pubmed/26009011
  • Dobbelstein M, Sørensen CS: Exploiting replicative stress to treat cancer. Nat Rev Drug Discov. 2015 Jun;14(6):405-23. doi: 10.1038/nrd4553. Epub 2015 May 8. (http://www.ncbi.nlm.nih.gov/pubmed/25953507)
  • Targeting tumour-supportive cellular machineries in anticancer drug development. Dobbelstein M, Moll U. Nat Rev Drug Discov. 2014 Mar;13(3):179-96. doi: 10.1038/nrd4201. Review. (http://www.ncbi.nlm.nih.gov/pubmed/24577400
  • Wienken M, Dickmanns A, Nemajerova A, Kramer D, Najafova Z, Weiss M, Karpiuk O, Kassem M, Zhang Y, Lozano G, Johnsen SA, Moll UM, Zhang X, Dobbelstein M (2015) MDM2 Associates with Polycomb Repressor Complex 2 and Enhances Stemness-Promoting Chromatin Modifications Independent of p53. Mol Cell. 2016 Jan 7;61(1):68-83. doi: 10.1016/j.molcel.2015.12.008.