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Job advertisement from May 28th, 2018   vacancy from: September 1st, 2018
Institute for Molecular Biology

The Institute for Molecular Biology opens a position in the group of Professor Dr. Markus T. Bohnsack for a

PhD student (f/m)
the position is available for 3 years, half-time | salary according to TV-L

The position is funded by a grant from the Deutsche Forschungsgemeinschaft (DFG) with the aim to better understand the dynamics and regulation of cellular RNAs and RNA-protein complexes.

RNAs and RNA-protein complexes (RNPs) play key roles in many cellular processes including various steps in gene expression. Our research focuses on understanding the biogenesis, dynamics and function of different classes of RNAs and RNPs in both yeast and human cells. We employ up-to-date methods from biochemistry, cell and molecular biology, among them several powerful high-throughput approaches such as (PAR-)CRAC/CLIP, RNA-seq and mass spectrometry. These methods are used to analyse the key roles of RNA helicases, their cofactors and other proteins in regulating RNP biogenesis and function, and how their dysregulation can lead to disease. Open projects in our lab aim to further explore these key topics of RNA/RNP biology. Furthermore, we are studying the important roles of RNA modifications in RNA and RNP dynamics and we offer projects investigating different aspects of “epitranscriptome” research. RNA modifications have recently been identified in diverse cellular RNAs and constitute highly dynamic/reversible regulators that both facilitate and fine-tune gene expression. These exciting discoveries are complemented by the finding that defects in RNA modifications or modification enzymes represent major contributors to disease and tumorigenesis.

Such interdisciplinary projects will be conducted within an enthusiastic and international team and involve collaborations with experts in the fields of medicine, structural biology and organic chemistry within the excellent environment of the Göttingen research campus and beyond.

We therefore seek excellent candidates with a Master in Biochemistry, Biology or related areas and experience in at least one of these fields (e.g. human cell culture, RNA-protein complexes, RNA mo-difications, genome-wide analyses) and who are interested to work on this topic in a dynamic team.

Please send the PDF file of your application including your CV, exam certificates and list of publica-tions, a summary of your current scientific work and names of three academic referees. Only applicants selected for interview will be contacted after the application deadline.

Women are especially encouraged to apply. Applicants with disabilities and equal qualifications will be given preferential treatment.

We look forward to receiving your application by June 27th, 2018

University Medical Center Göttingen
Institute for Molecular Biology
Prof. Dr. Markus T. Bohnsack
Humboldtallee 23
37073 Göttingen
Tel.: 0551/39-5968
Fax: 0551/39-5960
E-Mail: markus.bohnsack@med.uni-goettingen.de
Web: www.http://biochemie.uni-goettingen.de/index.php?id=679

Please send your application only via e-mail as a PDF-file.

Travel and application fees cannot be refunded or transferred.

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