Job advertisement from January 12th, 2018   vacancy from: January 12th, 2018
Klinik für Hämatologie und Medizinische Onkologie

The Clinic of Hematology and Oncology is seeking a highly motivated and experienced

Postdoctoral Research Fellow (male/female)
on behalf of the Chapuy Laboratory
Two-year initial contract with the option of extension, full time position | salary according to TV-L

Aggressive B-cell lymphomas are the most common lymph node cancers in adults and are characterized by a clinical and molecular heterogeneity. The Chapuy laboratory aims to personalize the diagnosis, prognosis and treatment options for patients with this hematologic neoplasias. Using functional and integrative genomics and epigenetics as well as other cutting edge technologies (Monti,Chapuy et al. Cancer Cell 2012; Chapuy Cancer Cell 2013; Chapuy et al., Blood 2016a) the workgroup elucidates coordinate genetic signatures of B-cell lymphomas with discrete biology that extend our unique understanding of the molecular heterogeneity of aggressive B-cell lymphomas at diagnosis and its change during treatment. The extracted coordinate genetic signatures yield testable hypotheses for subsequent mechanistic studies in in vitro and in vivo model systems, provides opportunities for the development of novel modeling approaches such as patient derived xenograft models (Chapuy et al, Blood 2016b) and eventual translation in the clinics, such as PD-1 blockade in B-cell lymphomas (Ansell et al., NEJM 2015; Nayak et al. Blood 2017).

We solicit applications from highly motivated candidates that hold either a PhD, a MD/PhD or equivalent degrees with experience in hematologic malignancies. The successful candidate is an experienced postdoctoral researcher with a completed graduate education in life sciences. The candidate has a stellar track record as evidenced by several first author papers (at least two) and has successfully applied for independent funding. Candidates with no more than one prior postdoc experience are encouraged to apply. The candidate has demonstrated experience in the interrogation and targeting of signaling and survival pathways of B-cell malignancies and excels in a wide variety of molecular- and cell biology methods, including lentoviral gene transfer, pooled CRISPR screens, etc.  Experience in mammalian cell systems is required and experience in genomics, epigenentics, immune escape and mouse modeling would be beneficial. Willingness to learn new field of research would be essential. The ability to plan and work intendent is equally essential as summarizing the work in presentations, meeting abstracts as well as manuscripts. A passionate and professional work attitude is expected. 

The successful candidate will assist the PI in running the workgroup and train and overview younger researchers, including medical students, undergraduate and graduate students, as well as junior postdocs and technicians. To this end, the candidate is an excellent team player, has preferentially some leadership and/or teaching experience and is an excellent communicator. Fluent spoken and written English is required. Candidates with a clear academic track have the option to write a postdoctoral thesis (Habilitation). The proven candidate will be provided with an option to extend his contract.

Interested candidates must submit their application composed of a curriculum vitae and a letter of motivation via email to before February 28, 2018.

Women are especially encouraged to apply. Applicants with disabilities and equal qualifications will be given preferential treatment.

We look forward to receiving your application by February 28th, 2018

University Medical Center Göttingen
Klinik für Hämatologie und Medizinische Onkologie
Univ.-Prof. Dr. med. Björn Chapuy
37099 Göttingen
Tel.: 0551/39-8695 or 0551/39-66327
Fax: 0551/39-8587

Please send your application only via e-mail as a PDF-file.

Travel and application fees cannot be refunded or transferred.